Let us consider some of the excellent female candidates when the next UN Secretary General is appointed

http://www.womansg.org/

We are approaching the end of the current term of the UN secretary general.  Let us consider some of the excellent female candidates for the position!

Every past SG has been a male.

Who wants a 24 hour work week? If workers wages rose as fast as worker productivity, we would have one.

http://www.businessinsider.com/growing-productivity-stagnating-compensation-2011-3

If you gave the gains in worker productivity since 1950 to the workers, and not just the bosses, we could make the same living we have today on between 24 and 32 hours a week.

Basically worker pay has stagnated since Reagan, but worker productivity is 180% of what it was.

Thus as it ever was. All too often the papers talk of record punitive actions for guilty elites, but the sentences do not hold up on appeal.

  I want to talk about one trend, seen in two places, that has to end.  The idea is that someone does something really bad, and enough people get upset that something has to happen.  So something dramatic is done that makes the papers, people feel good about it, and then it gets quietly undone on appeal.

  Take for example Scooter Libby, Chief of Staff of Vice President Cheney, who was convicted of obstruction of justice in the Valerie Plame matter.  Basically President Bush was accused of outing an American secret agent as political revenge against her husband.  Scooter took the fall.  Bush commuted his sentence without pardoning him, because a felony conviction meant not being able to practice law was punishment enough:

http://www.nytimes.com/2009/02/18/us/politics/18cheney.html

Yeah for justice!

Fast forward a few years, and he gets pardoned:

http://nymag.com/daily/intelligencer/2013/03/scooter-libbys-triumphant-return-to-politics.html

His punishment was effectively 3 years off work with pay.

Or take the example of the Exxon Valdez, worst oil spill in forever.  The drunk captain gets huge fines that make all the papers:

Here you see the EPA saying Exxon will pay "One Billion Dollars" with a tone that almost sounds like Austin Powers:  http://www2.epa.gov/aboutepa/exxon-pay-record-one-billion-dollars-criminal-fines-and-civil-damages-connection-alaskan

Then the SCOTUS cuts it, and cuts it again, and as of 2011 Exxon is on the hook for about $400 million.

http://www.faegrebd.com/2881

So the thing is, we need some sort of calendar system to remind us to get outraged about past items we think were settled because outrage fatigue for the current crap is no enough.

Sigh.

As an aside, BP appears to have had a role in breaking the law, making the spill far worse than it would have been.  You remember good old BP, the folks who brought you the deepwater horizon?

http://www.truthdig.com/report/item/25_years_after_exxon_valdez_the_hidden_culprit_was_bp_20140323

I feel for them, I really do.  I remember when their chief executive Tony Hayward issued an apology for the Deepwater Horizon.  He had to take time out from sailing to get some updates, and had this to say: "We're sorry for the massive disruption it's caused their lives. There's no one who wants this over more than I do. I would like my life back."

Truth and Reconciliation, why we should not pardon someone who has not confessed or been convicted.

  I've posted in other places about how pardoning Richard Nixon without making him confess allowed him and Henry Kissinger to regain influence in American politics decades later.  The other day, I was reading a post on Stonekettle Station, a blog by Jim Wright, which brought up the subject.  Before I get into my thoughts, just let me say, I regularly read Stonekettle Station, Jim Wright is a smart fellow, and his words are worth considering. I would encourage everyone who cares about American politics to read that post, and consider tossing him a few dollars, I do.  The post that got me thinking about this is located here:
http://www.stonekettle.com/2015/03/the-second-coming-of-richard-millhouse.html

  So here's my take on this.  President Lyndon Johnson's papers were unsealed recently after 40 years along with tapes from the Whitehouse phone system and so on. It shows that Richard Nixon, who was running for president, arranged for Henry Kissinger, President Johnson's advisor in the "Paris Peace Talks", to tell the S Vietnamese to pull out of the talks.  Presumably because it would allow Nixon to win, and Nixon would give them the war they wanted.  When they pulled out of the peace talks, Nixon won, and gave them their war, and an additional 20,000 Americans died while the war continued.
  Just think about that for a while, and let it sink in.  20,000 Americans died, so Nixon could become the next Republican president.

  You might remember that when Nixon later became president he resigned over a burglary at the Watergate Hotel to steal some information from the Democrats.  Everyone thought it was election information, but it appears to have been an attempt by Nixon to learn what President Johnson knew about Nixon's role in sabotaging the peace talks.  You see, for Nixon to arrange for someone to sabotage matters of state would be treason, a capital offense.

  That sounds kind of like 47 Senators who sent a letter to Iran,   When S. Vietnam pulled out, the US stayed in Vietnam for another 7 years, killing 20,000 people. I've covered this half a dozen times, the modern Republican party (since 1948 or so) are largely self-concerned pricks, who would sabotage their mother for a vote. And these bastards in congress, these 47 Moronin, are doing it again.
But I am digressing from my main point. 

  I think Nixon resigned not over concerns about getting caught instigating a break-in, he resigned over fears they had proof he committed treason, for which he could have been tried, and if convicted put to death. But it never happened, he was pardoned without being forced to divulge his crimes. And that process, pardoning something for which the person never confessed, or for which they were never convicted, is a poison in American politics.

  I propose, that if you want to get pardoned, you need to be pardoned for specific actions.  This means you have to either confess the thing you are being pardoned for, so they are fully disclosed and people can understand the crime, or you have to go to court, be convicted, and get a pardon for the thing you were convicted of.  I got the idea from the South African "Truth and Reconciliation Commission"  In South Africa it really would have to try everyone, so they had them write up their crimes, and they forgave what was documented.  If you later did more bad stuff, well, trials for everyone!

  This modern notion of letting people go free because it would be too disruptive to prosecute them is poison, and has to end.

Epigenetics, how our genes can been turned off or on in response to a changing environment.

In followup to my earlier post, here is a nice discussion on the basics of epigenetics.

http://www.pbs.org/wgbh/nova/genes/

Squid can tweak how their genes express proteins on the fly.

The title kind of sucked, but the concept is really cool, I had no idea it happened in nature:

http://www.sciencedaily.com/releases/2015/02/150212114327.htm

TLDR: Squid can edit their RNA on the fly, which controls which proteins get made.  This effectively allows for one set of genes to make a bunch more proteins that would otherwise be possible.

Let us review.

So long ago when we first learned about evolution and genetics, Darwin wrote a paper about evolution through the inheritance of traits.  The basic idea was that genes passed down from mom and dad determined if an organism was a good fit for its environment.  If it was a good fit, it had lots of kids, bad fits failed to reproduce.  Over time random mixing of genes (via sex) and the occasional mutation, would result in newer organisms, some of which were more fit.  DNA is a chemical in the cells of the body.  It stores all the information about how to make you, and how to keep you operating.  It works by splitting in half life a zipper, making some RNA, and the RNA chemicals make proteins, which are the building blocks of you!  (I am grossly over simplifying)

But we know so much more now.

 - We discovered genes swapped back and forth between X chromosomes, adding even more mixing than simply sperm mixing with egg.

 - We discovered the viruses that can make us sick by forcing us to replicate their genetic code, can also splice themselves into our DNA.

 - We discovered the entire field of epigenetics, the idea that chemicals called methyl groups would wrap around the genome and prevent it from expressing RNA.  Using the epigenome an organism can silence certain genes and prevent them from coding proteins.  For example, if a virus inserted its code into our genes, we could silence those genes and bring redundant backups into use.

So the latest in this article, is that squid can edit their RNA on the fly.  I had no idea this happened. The title stinks, but the idea is genes have DNA that encodes RNA that encodes protein, and sometimes the RNA is changed in a specific way, so the proteins get made a little funny. But in squid, around 60% of the protein is sometimes made funny, and it makes us wonder why. This cannot be on accident, but how does it work and how the organism benefit from it.

Good stuff.

Focused ultrasound works on mice with alzheimer's disease.

Great news!

http://www.sciencealert.com/new-alzheimer-s-treatment-fully-restores-memory-function

  In summary, alzheimers is thought to be caused by plaques building up in the brain, and a protein goop that makes it hard for nutrients and other essential things to move around to where they are needed.  This focused ultrasound treatment opens up the blood-brain barrier for a few hours, letting in microglial cells that remove waste and do cleanup.  In mice, the procedure was non-invasive and returned memory to 75% of recipients.